At the end of the first session, the doctor performed the painless cheek swab to submit as a sample for the genetic tests that would be a crucial help in guiding appropriate treatment approaches.
A Precision Medicine Approach to Social Anxiety
The following week, they met to discuss results of the swab. Grace’s parents were relieved to see that there were several over-the-counter supplements that could be introduced prior to medication, including magnesium supplementation for Calcium Channel variants and Omega 3 Fatty Acids for Sodium Channel variants. Their psychiatrist explained that the Calcium Channel and Sodium Channel are also known as “The Roller Coaster genes”, which due to Grace’s unique gene variants could be playing a role in her emotional swings during the day. The psychiatrist also explained the role of MTHFR in mental health. MTHFR is an enzyme that converts folic acid to L-methylfolate, an important cofactor in creating the neurotransmitters that allow a child to stay calm and focused. Due to Grace’s unique genetic variants, she was only converting about 50% of the folic acid to l-methylfolate, leading to a significant supply chain issue in producing serotonin, norepinephrine, and dopamine. Armed with this important information, they created a back-up plan to introduce an SSRI antidepressant if needed, given that the two long alleles in her SLC6A4 gene suggested she may have a positive response to this particular medication.
One month later, Grace and her parents arrived at Potomac Psychiatry for their first follow-up session. Entering the room, the psychiatrist noted a significant change in not only Grace’s anxiety, but that of her parents as well. Grace had connected with a local CBT therapist and was learning to connect her thoughts, feelings, and behaviors. She was better at communicating her feelings with her family and had identified triggers to her anxiety in the school setting. Her teacher made modifications in the classroom, and Grace started to thrive. Grace’s parents were thrilled that by incorporating supplements and individual therapy, they were able to avoid adding anti-anxiety medications—and the results of her genetic testing gave them confidence that, if and when additional treatments were needed in the future, they’d be precisely tailored to Grace’s unique needs and would likely have a far better impact than her first medication experience.
Dr. Mark A. Novitsky Jr.
Mark A. Novitsky Jr., MD is a Dual Board Certified Child and Adolescent/Adult Psychiatrist with experience in clinical and forensic practice. Dr. Novitsky uses a variety of psychotherapy techniques, as well as medication management when necessary, in the treatment of children and adolescents. He highly values an ongoing collaborative relationship with parents. His psychotherapy techniques include cognitive behavioral therapy (CBT), play therapy, and parent management training. Following his training in child psychiatry, he sought out formal Cognitive Therapy training with children and adolescents through “The Beck Initiative”, sponsored by The Aaron T. Beck Center at the University of Pennsylvania, where Dr. Aaron Beck first created CBT.
Dr. Novitsky has served for several years as corporate medical director for Philadelphia’s fastest growing non-profit by serving children experiencing emotional, behavioral, and academic challenges. His extensive clinical experience includes, but is not limited to:
- Childhood trauma/Post-traumatic stress disorder (PTSD)
- Attention Deficit Hyperactivity Disorder (ADHD)
- Depressive disorders, Bipolar disorder and other mood disorders
- Anxiety Disorders and Obsessive Compulsive Disorder (OCD)
- Oppositional Defiant Disorder and Conduct Disorder
- Autism Spectrum Disorder
- Learning Disorders
- Substance Use Disorders
- Intellectual Disability
Dr. Novitsky is an adjunct clinical faculty member at Temple University Hospital’s Department of Psychiatry and Behavioral Science and is the clinical preceptor for 2nd year residents Child and Adolescent rotation. He educates psychiatry residents and 4th year medical students about the intricacies of the mental health world and how it interfaces with other inter-agency supports that comprise a court-involved youth’s comprehensive treatment. He has been the recipient of a grant for his research, has been published in peer-reviewed journals, and has presented at national conferences.
View complete curriculum vitae for Mark A. Novitsky Jr., MD
- Diagnosis and Prognosis
- Child and Parental Assessments in Custody and Divorce Cases
- Treatment Recommendations
- Pharmaceutical Claims