LIVING WITH ADHD

June 30, 2010

In the United States, an estimated 4.4 percent of adults ages 18-44, 4 percent of children ages 4-8, and 9.7 percent of children ages 9-17 experience symptoms and some disability from ADHD. As such, ADHD is one of the most common of all psychiatric disorders. It is also among the most treatable.

Research has established that ADHD is a neurobiological condition with a likely genetic component, wherein critical circuits in the frontal cortex of the brain responsible for sustained attention, organization, planning, and various other executive functions are not functioning properly. The speed and efficiency of information processing is inconsistent, and compromised. These circuits mainly rely upon two neurotransmitters to function (dopamine and nor-epinephrine), and most medications used to treat ADHD increase the availability of one or more of these two transmitters. Additional treatments typically include education, cognitive/behavioral techniques, and cardiovascular fitness exercise. Exercise activates the frontal cortex in all age groups, and increases levels of both dopamine and nor-epinephrine.

If you are a patient suffering from ADHD, or a family member living with someone with ADHD , what is the impact on your life?

For the patient with ADHD, living in reality feels like a “discontinuous experience.” Because they are frequently distracted by wandering thoughts, excessive daydreaming, and external motion and sounds in the environment when trying to focus on a task, they miss out on a number of important environmental cues, and struggle harder to learn new information. This has nothing to do with their level of intelligence, as I have treated many outstanding students, executives, and professionals with ADHD. These highly capable individuals have become overwhelmed and emotionally depleted from the challenge of processing increased volumes of information. Certain information from the environment therefore never “gets inside” their brain, and therefore is unavailable to be processed, particularly when their “supply” of information processing is exceeded by the “demand” to process information while at school or in the workplace.

A useful analogy to assist in explaining this experience is to imagine for a moment that your computer suffers from ADHD. As a result, an average of one out of every ten keystrokes that you type on the keyboard never register in the computer – that portion of the data never gets entered. In addition, the keystroke data that is “dropped” on the way in is random and unpredictable. The computer then inconsistently processes the information that has been entered – at times with the latest Intel Core 2 Duo Processor, and at other times with an Intel 386 microprocessor designed 20 years ago. The end result is that this computer could run Windows 95 just fine, but what about Windows Vista? For simpler processing tasks it would function just fine, but as processing complexity increased, it would begin to function poorly, if at all. How well would the computer function with its varying processors that are commanded to process incomplete information? What would the work product (for example the text or financial information you have created), look like when displayed or printed out?

While our brains may function in certain respects like a computer, a machine lacks a heart. Having ADHD is not just cognitively challenging, it is emotionally painful, as learning becomes more of a struggle, social cues are missed, distractibility is interpreted as a “lack of interest” or “rudeness” by others, and self-esteem is diminished over time. Anxiety and depression may set in. Patients with ADHD are twice as likely to develop a major depressive disorder, significant anxiety disorder, or substance abuse problem as the general population. Social development is slower and more challenging due to missed social cues and delayed brain maturation. Symptoms may be masked by high intelligence and a strong work ethic, which provide for a temporary “work around” the ADHD processing deficits. But as the complexity of life increases at certain transition points (for example moving from middle school to high school; taking standardized tests such as the SAT, LSAT, medical boards or bar examination; or receiving a significant promotion at work) the attentional system may become overwhelmed, emotional symptoms become more pronounced, and psychiatric care becomes necessary.

Living with a loved one suffering from ADHD is also emotionally painful. Life with someone who frequently misplaces or loses belongings, forgets to accomplish chores or duties that were seemingly explained and understood, procrastinates, is disorganized leading to messy bedrooms and assignments, acts impulsively due to a lack of planning, and is distractible in a way that seems like “they just don’t listen,” can lead to feelings of anger, frustration and exasperation. There is also the experience of sadness in watching a loved one struggle with some of the routine demands of everyday life.

The good news is that ADHD is highly treatable, and that medication, education, exercise, and cognitive/behavioral therapy can be “game changing.” Not uncommonly a stimulant medication can improve symptoms 80% to 90% by improving the speed, efficiency and consistency of information processing. Typically the most stubborn symptoms to treat are procrastination and disorganization, which often respond to higher doses of the stimulant (which mainly boosts dopamine levels), or require the addition of Strattera (which boosts nor-epinephrine). Simple organizing techniques such as the use of a PDA, a spiral notebook (not Post-its), and habitually returning personal belongings back to the same location, can be helpful. Specialized neuropsychological evaluations, psychotherapy and educational services, providing tangible techniques to improve study skills and workplace performance, can also bring about increased feelings of mastery and success, and result in improved self-esteem. Effective treatment of ADHD not only enriches the life of the person suffering from the condition, it also enhances those important relationships at work and at home.

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In a prior blog posting entitled “The Psychiatrist as Psychotherapist” there was a reference to the privilege of being trained during “The Golden Age of Psychiatry.”As the following story illustrates, This Golden Age had a somewhat turbulent beginning…

When I completed my medical school education at Georgetown in 1975, and prior to beginning residency training at the psychoanalytically-oriented program at Tufts New England Medical Center in Boston, I traveled to London to learn about the emerging and exciting field of psychopharmacology. This was a conscious decision to round out my education and become exposed to new ideas that I would not receive in Boston, as the Tufts program focused on providing some of the top psychoanalysts in the country teaching residents how to perform intensive psychotherapy of hospitalized patients as well as outpatients. As the Tufts program lacked a psychopharmacologic curriculum, I felt that I needed to go to London.

Upon arriving I was surprised to learn that there was a severe dichotomy between the teachings of the psychopharmacologists, and those of the psychoanalysts. In short, not only did they vehemently disagree as to the origin and treatment of serious emotional problems, there appeared to be a lack of respect for or synthesis of differing points of view.
Nonetheless, I was there to learn about how medications could assist in restoring the brain’s emotional functioning, and I excitedly engaged with my professors at England’s Maudsley Hospital and Institute of Psychiatry, who were pioneers in the research and clinical use of medications to treat emotional disorders. It was a wonderful experience that I treasure to this day.

Now flash forward several months to the beginning of my residency training at Tufts. I was in my first month of the program, and I was on weekend emergency call at the New England Medical Center emergency room. A nineteen year old young man came in who was in a highly agitated manic state. Armed with my newfound European knowledge about the use of Lithium to treat Manic Depressive Psychosis (later renamed Bipolar Disorder), I admitted him to our inpatient unit and confidently placed him on Lithium. I was really proud of myself. That feeling of pride would turn out to be very short-lived.

On Monday I received an urgent call from the Director of Residency Training at Tufts, who insisted upon seeing me immediately. Nervously entering his office (he was a world famous psychoanalyst), he sat me down and proceeded to rake me over the coals for placing my patient on this “unknown” and “dangerous” substance, Lithium, which I had no right to do, particularly since I hadn’t discussed it with my supervisor (who as a social worker could not advise me on prescribing any medication, so I didn’t see much sense in that requirement).
I was crushed, and when he dismissed me from his office I was convinced that he would terminate me from the program. Shaken by the experience, and looking for an immediate reality check and some support, I went to see one of my supervisors (also a world famous psychoanalyst, with a kindly demeanor) and asked him whether I would be terminated, and what I needed to do to restore my good graces with the Director. My supervisor patiently listened as I described my experiences in London, and what I had learned that I simply tried to apply to my poor manic patient to alleviate his suffering. The supervisor told me that he would intervene with the Director on my behalf, and asked if I could provide him some articles on “that Lithium medication” as he was curious about it. (Interestingly, Lithium was first used to treat patients in Australia by John Cade in 1949 , and this was 1975, one year after the FDA had approved it for use in the United States, so it was not as if I was some wild-eyed radical psychiatrist).

Relieved, I left his office and was not bounced out of the program. I provided him two articles on the use of Lithium, and we discussed how the Lithium, combined with my seeing my manic patient five times per week in intensive therapy, worked together to help him. Two years later Tufts brought in a new Department Chairman- trained as both a psychoanalyst and a psychopharmacologist. I went from being the radical first year resident to being selected as Chief Resident in my third year, and a member of the medical school faculty the following year.

The Golden Age was underway.

Of course what was interpreted as a reckless and a bold move by me at that moment in history is now routine practice, and today treating a manic patient with psychotherapy alone would be considered malpractice. The Biopsychosocial Model of psychiatry is in full bloom – integrating a number of knowledge bases and databases to optimize the care of our patients.

It was my great privilege to go to London to learn psychopharmacology, and an even greater privilege to train in psychotherapy under the tutelage of top psychoanalysts in Boston. I feel grateful for these experiences every day, and remember with fondness and humor my turbulent initiation into The Golden Age of Psychiatry.

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